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张锋最新Cell论文:利用AI工具,揭开CRISPR-Cas13系统进化之谜
CRISPR-Cas 系统是细菌和古菌的适应性免疫系统,能够抵御病毒和可移动遗传元件的入侵。尽管 CRISPR-Cas9 和 CRISPR-Cas12 系统的 DNA 靶向机制已经被广泛研究,但 RNA 靶向的 CRISPR-Cas13 系统的进化起源,目前仍然不清楚。 2025年2月18日,张锋团队在国际顶尖学术期刊 Cell ...
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