The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a ... of Syk tyrosine kinase binding to membrane immune receptors and ...

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process ...

All JAK kinases are tyrosine kinases and all are also Janus ... "Janus kinases bind to class I and II cytokine receptors, activating signaling and regulating gene transcription," writes Dr ...

ERBB receptors are regulated by their own intrinsic properties as well as by external associated proteins. What is regulation, where does it occur on the receptor, and how do scientists study it?

Sorafenib is an oral multikinase inhibitor that inhibits tumor growth and proliferation by interfering with several receptor tyrosine kinases involved in the pathogenesis and perpetuation of ...

All JAK kinases are tyrosine kinases and all are also Janus ... Zoler and colleagues have demonstrated that receptor-binding competition among members of the Janus kinase family may explain ...