As monotherapy, the valproic acid salts have been demonstrated to be effective in the treatment of several types of epileptic seizures, both primary and secondarily generalised seizures as well as ...

Valproate was recommended for primary generalized seizures, although these are rare in the elderly. It seems reasonable to consider some newer AEDs, such as levetiracetam, given its inert ...

A woman with epilepsy has accused the UK's drug safety regulator of failing patients. Kristi McDonald, from Southmoor, ...

Children of mothers who took certain anti-seizure medications while pregnant do not have worse neurodevelopmental outcomes at age 6, according to a long-running study.

Children of mothers who took certain antiseizure medications while pregnant do not have worse neurodevelopmental outcomes at ...

Sodium valproate was already known to make it more difficult to father a child. But the MHRA says this is usually reversible after the drug is stopped. Chief executive of the Epilepsy Society ...

"The bottom line," Pack says, "is that I tend not to prescribe valproate as a first-line drug for most women with epilepsy who are in their reproductive years. That's not to say that valproate is ...

Children of mothers who took certain antiseizure medications while pregnant do not have worse neurodevelopmental outcomes at ...

The drug rapamycin could prevent the epilepsy medication sodium valproate from causing developmental problems during ...

Christine Coley says she was not told of the risk of getting pregnant while taking the epilepsy drug Christine Coley was prescribed sodium valproate for epilepsy when she was trying for her fourth ...

The mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of ...