We are also actively investigating the regulation of Syk tyrosine kinase binding to membrane immune receptors and other signaling proteins. Syk recognizes doubly phosphorylated regions of the receptor ...
which is involved in interactions between two receptors within the cell membrane, and an intracellular domain that contains the tyrosine kinase enzymatic activity. The EGFR autocrine pathway ...
Novel macrocyclic heteroaryl derivatives acting as non-receptor tyrosine-protein kinase TYK2 and/or JAK1 and/or JAK2 inhibitors have been reported in a Hangzhou Highlightll Pharmaceutical Co. Ltd.