The tumor microenvironment (TME) -- the space surrounding a tumor -- plays a critical role in interactions between cancer and immune cells. Cancer cells can reshape the TME to their advantage ...

As we observe World Cancer Day today, let us look at some of the trends in cancer therapeutics expected to improve cancer ...

Researchers from Japan, discover mitochondrial transfer from cancer cells to immune cells and metabolic reprogramming of the tumor microenvironment as a key immune evasion strategy. Targeting ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Russian mRNA cancer 'vaccine' shows promise in pre-clinical trials, part of growing immunotherapy trend in cancer treatment.

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

T-cell therapy represents a groundbreaking advancement in the field of immuno-oncology. This innovative treatment involves ...

Louis, Missouri 63110, USA. To fill this knowledge gap, Ikeda and colleagues obtained tumour-infiltrating T cells and cancer cells from human tumours that were surgically removed and sequenced the ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

This is because the primary tumor continuously releases cancer cells into the blood. These circulating tumor cells (CTCs) can join together into small clusters of up to a dozen cells and settle in ...

Background: Cancer stem cells (CSCs) have been characterized to be responsible for multidrug resistance, metastasis, recurrence, and immunosuppressive in head and neck squamous cell carcinoma (HNSCC).