The taxanes exert their cytotoxic effect by binding tubulin, stabilizing the microtubule and inhibiting its disassembly, ultimately leading to cell death by apoptosis. Although there is no maximum ...

A team of geneticists at the Max Planck Institute for Psycholinguistics, in The Netherlands, has found a genetic variant that codes for a tubulin protein that may be partially responsible for ...

The project was funded by the Swiss National Science Foundation, a David and Lucile Packard Fellowship for Science and Engineering, a Burroughs Wellcome Fund Investigators in the Pathogenesis of ...

A seasoned industry leader, Mr. Hata brings a track record of building innovative companies that have delivered breakthrough medicines for ...

The FDA granted a fast track designation to ALE-P02 for patients with CLDN1-positive squamous solid tumors. The FDA granted ...

The development of maternal egg cells is pivotal for survival—but also precarious. During meiosis, the DNA-containing ...

In 1896, in his seminal work “The Cell in Development and Inheritance”, the cell biologist Edmund B. Wilson formulated a ...

In 2023, we published another article about CRSP in Cell Biology Education – A Journal of Life Science Education. That article assesses the impact of shifting research modalities and their impacts on ...

Androgen deprivation is the mainstay of advanced prostate cancer treatment. Despite initial responses, almost all patients progress to castration-resistant prostate cancer (CRPC). The ...