T cells are a type of white blood cell that is central to your immune defense. There are four types which serve different functions: This article will guide you through how CD4 and CD8 cells interact, ...

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity. Oncogene , 2024; DOI: 10.1038/s41388-024-03191-1 Cite This Page : ...

drugs targeting TIGIT had become sought-after assets in the pharma industry, on the promise that they may inhibit anti-tumour responses that down-regulate the activity of T-cells and provide an ...

总之，这些发现揭示了一个先前未知的免疫细胞新亚群的动态相互作用，即tigit+treg-tgf-β-cd226+cd8+t，该作用轴不仅调控免疫环境的稳态，还为t1d提供 ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...

Combining the molecular signatures with immunophenotypic profiles revealed that cytotoxic CD8 ­T cells­ were associated with SGS. Further, we observed the activation of SGS in cytotoxic CD8 T cells ...

TIGIT – short for T cell immunoglobulin and ITIM domain – has emerged as a potential inhibitor of anti-tumour responses, down-regulating the activity of T cells and natural killer (NK ...