thymine and uracil are all pyrimidines: single rings. To maintain its orderly structure, single rings on one strand can only bond with double rings on the other. This keeps the DNA molecule in the ...
In genetics, it has generally been accepted that each gene has one transcription initiation site, located downstream of a core promoter region and typically around a TATA box — a DNA sequence rich in ...
Animal models expressing loss-of-function mutations in mitochondrial DNA enable the investigation of mitochondrial gene function and related disorders. In a recent study, scientists from Korea ...
Molecular grunt work When a DSB happens in DNA, it's like a load-bearing beam in a building breaking. A careful, precise repair is needed to ensure the building's—or the DNA's—stability. The ...