A man in his late 50s presented to the emergency department with 4 weeks of acute-onset, severely limiting short distance claudication in his right lower extremity. A CTA showed a popliteal artery ...
Histology was performed on arterial regions that were injured by balloon. Six rabbits (67%) developed thrombus. Histological correlation confirmed all thrombi (100%) detected with OCT, with no other ...
Results Thrombin activity eluted from clots of AF origin decreased significantly with time in contrast to steady levels eluted from AS origin thrombi (P<0.0001 by repeated measures ANOVA). The Cr ...
Macrophages and T cells were scattered in the superficial layer of the intimal thickening, and these were occasionally associated with organization of fibrin thrombi. Proliferating smooth muscle cells ...
TBO-309 is under clinical development by ThromBio Holdings and currently in Phase II for Acute Ischemic Stroke. According to GlobalData, Phase II drugs for Acute Ischemic Stroke have a 47% phase ...
Carotid artery free-floating thrombus (FFT) is a rare but clinically significant cause of embolic stroke. Treatment has historically been confined to carotid surgery or best medical therapy, with ...
Magnetic resonance imaging (MRI) is a non-invasive biomedical imaging technique that uses a strong oscillating magnetic field to induce endogenous atoms such as hydrogen, or exogenously added ...