The primary function of Th17 cells appears to be the clearance of extracellular pathogens during infections. However, Th17 cells also promote inflammation and have been implicated in the pathogenesis ...

Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by acute deterioration of liver function ...

Liver failure encompasses a range of severe clinical syndromes resulting from the deterioration of liver function, triggered ...

However, their role in AAD remains to be established and inclusion of Th17 in the model represented by Figure 3 is highly speculative. Treg cells are able to inhibit autoimmunity and protect ...

eye-center.org Results ATRA synergised with TGF-β to induce Foxp3 + T regulatory cells (Treg) and reciprocally inhibited development of IL-17-producing T helper cells (Th17) induced by TGF-β and IL-6.

Objective Although Th17 cells have been increasingly recognised as an important effector in various autoimmune diseases, their function in the pathogenesis of Sjögren's syndrome (SS) remains largely ...

3 An important pathological process increasingly recognised as driving intestinal inflammation and autoimmunity is the loss of immune homeostasis secondary to qualitative or quantitative defects in ...

FOXP3 + regulatory T cells (Treg cells) are key for immune homeostasis. Here, we reveal that nuclear receptor corepressor 1 (NCOR1) controls naïve and effector Treg cell states. Upon NCOR1 deletion in ...