Th17, Tregs and neutralizing Abs). Rightly so, however, from the results of the different GWASs summarized in the present article, a largely unexplored or poorly understood role of innate immunity ...
Keywords: Treg, cell therapy, specificity, functionality, stability, manufacturing, biomarker, clinical trial, regulatory, safety, combination Important Note: All contributions to this Research Topic ...
Quell’s Treg platform induces sustained expression of FOXP3. Image credit: Shutterstock/ Vink Fan. AstraZeneca has exercised an option to license a cell therapy from Quell Therapeutics, resulting in a ...
This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...
Correspondence to Dr Rainer H Straub, Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine, University Hospital Regensburg, Biopark I, Josef Engert ...
Here, in two phase lb trials, the authors show that rezpegaldesleukin, a Treg-selective pegylated IL-2, is safe and improves symptoms in patients with atopic dermatitis or psoriasis.