Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...
In the 1930s, Muller was surprised to note that telomeres were strangely resistant to mutagenic X-rays. Why are the unique properties of these chromosomal "end caps" so important? Thus ...
During the early stages of meiosis, telomeres assemble into a structure that looks like the stems of a floral bouquet — the telomere bouquet. The main role of the telomere bouquet was thought to ...
But a new study finds that, despite this apparent rebirth, younger forests may not offer those birds the same quality of ...
Cells use homologous recombination to stitch double-stranded breaks (DSB) back together and the enzyme telomerase to cap exposed ends of a DNA strand with a repetitive DNA sequence called a telomere.
Researchers at The University of Texas MD Anderson Cancer Center have identified a potential breakthrough in the fight ...
“The novelty and merit of this work is that the authors demonstrate, for the first time, that [telomere transcription] occurs in response to physical exercise in a physiological system—human muscle,” ...
“This is the first mouse model with truly humanized telomeres because telomerase isn’t expressed in adult tissues in this model,” said Jiyue Zhu, PhD, professor, college of pharmacy and phar ...