The recently-revealed Teenage Mutant Ninja Turtles: Tactical Takedown uniquely (and depressingly!) starts things off with Splinter and Shredder already having been killed. For most of the Teenage ...
It is difficult to suggest how many runs exactly are needed to beat Shredder, but the aforementioned 7–8 hours of gameplay time is enough to improve your stats and beat TMNT: Splintered Fate.