This important study uses the Jurkat T cell model to study the role of Formin-like 1 β phosphorylation at S1086 on actin dynamics and exosome release at the immunological synapse. The evidence ...
which are designed to draw T cells into close contact with tumor cells. Clasp says that the resulting immune synapse is highly similar to a natural HLA molecule-T cell receptor interface, triggering T ...
A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA ... Focusing on the immune system's T cells, the researchers showed that CISA could be ...
T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...
Matt Levine is a Bloomberg Opinion columnist. A former investment banker at Goldman Sachs, he was a mergers and acquisitions lawyer at Wachtell, Lipton, Rosen & Katz; a clerk for the U.S. Court of ...
The extracellular molecular organization of the individual CD3 subunits around the αβ T cell receptor (TCR) is critical for initiating T cell signaling. In this study, we incorporate ...