Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

引言人类胚胎发育的过程犹如一幅精妙绝伦的生命画卷，从一个微小的受精卵开始，短短数周内通过复杂而精准的细胞分裂与分化，演变成具有初步结构和功能的胚胎。这一过程不仅展现了生物学的奥妙，也蕴藏着生命起源的答案。尽管人类对自身的了解日益深入，胚胎发育的早期阶 ...

2024年11月19日，香港城市大学生物医学工程学系史鹏团队在期刊《Nature Communications》上发表了题为“Single-cell encoded gene silencing for high-throughput ...

Researchers have developed TRISCO, a cutting-edge microscopy method that enables 3D RNA analysis in whole, intact mouse ...

This basic research study presents useful data concerning the menstrual fluid composition and its potential for endometriosis biomarker research. However, despite solid bioinformatics analyses, the ...

A recent study leveraging single-cell RNA sequencing (scRNA-seq) has uncovered vital molecular mechanisms underlying NB's progression and metastasis, shedding light on potential therapeutic targets.

By understanding more about the cycle of inflammation, it might be possible to find new ways to prevent or treat this in IBD.

Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others ...

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables ...

Researchers at Saint Louis University's School of Medicine say T-cell dysfunction is leading to an increased risk of cancer ...

T helper (TH) cells are essential immune cells that help other immune cells function effectively. When activated in response ...