Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Researchers have developed TRISCO, a cutting-edge microscopy method that enables 3D RNA analysis in whole, intact mouse ...

Researchers developed SCimilarity, a groundbreaking metric-learning framework, to rapidly analyze and compare single-cell data across tissues, diseases, and experimental conditions. This tool enables ...

Our findings show where RNA editing takes place and which factors regulate it, allowing us to understand how RNA editing can ...

Researchers have analyzed the entire mouse intestine, mapping gene expression and cell states and location in the healthy gut and in response to perturbations such as inflammation. They identified ...

One of the scientists' special strategies was to investigate cell states using the new method of single-cell RNA sequencing.

If you’ve ever lost weight only to watch the pounds creep back on, you’re not alone. Now, scientists have uncovered a ...

A section of mouse intestine with colored fluorescent tags under a microscope. Image: Michael W. Davidson/Florida State University/Zeiss Microscopy At a glance: Scientists mapped gene expression and ...

Researchers mapped gene expression across the mouse intestine, revealing its stability and adaptability to changes like inflammation. The study identified immune-controlled regions and resilient ...

引言胃肠道在人体中扮演着至关重要的角色，它不仅是营养吸收的主要场所，更是免疫防御的重要前沿。然而，随着现代社会生活方式的变化，克罗恩病、溃疡性结肠炎等炎症性肠病的发病率持续上升，给患者带来了巨大的痛苦和不便。这些疾病不仅影响到人们的日常生活质量，还与 ...