Back pain caused by worn-down vertebral discs is called degenerative disc disease. In a young and healthy back, rubbery discs between the vertebra provide height and allow bending and twisting. As a ...

Osteoarthritis (OA): A degenerative joint disease characterized by the breakdown of cartilage and underlying bone. This Nature Research Intelligence Topic summary is one of 30,000 created with ...

In shoulder osteoarthritis (OA) – also called degenerative joint disease – your cartilage and other joint tissues gradually break down. Friction in the joint increases, pain increases and you slowly ...

Background Pathomechanisms of degenerative joint diseases such as osteoarthritis (OA) ultimately result in the breakdown of cartilage tissue. To date, the exact underlying mechanisms of both cause and ...