In mammals, pyruvate is the primary substrate for lactate production. It plays a critical role in metabolism by linking glycolysis, where it is produced, with the mitochondrial oxidative ...
Integration of RNA-seq and AGO2 eCLIP-seq identified miR-1 target genes involved with glycolysis and pyruvate metabolism. The loss of miR-1 in skeletal muscle induced cancer-like metabolic ...
MP is a membrane-permeable pyruvate derivative that is capable of activating mitochondrial energy metabolism in human lung carcinoma A549 cells and murine squamous carcinoma SCCVII cells. Pretreatment ...
The enhanced PDH activity promotes an increase in mitochondrial pyruvate flux, and this enhanced energy state gates memory consolidation, thereby enabling LTM formation. After 3 h, the lasting effect ...
Steiner, MD, Instructor, School of Medicine and Assistant Professor, School of Nursing, Oregon Health and Science University, Portland, Oregon; Chief, Division of Metabolism, Departments of ...
Metabolism is the process by which your body turns food into energy through chemical reactions in your cells. Your metabolic rate is a measurement of how many calories (units of energy) your body ...