Therapeutic outcomes in patients with TBM may be closely linked to both INH dosage and NAT2 gene polymorphism (9). Tailoring INH dosage based on NAT2 polymorphism may optimize treatment regimens, ...

A single gene in the shorebird species known as ruffs controls the levels of testosterone in males, and this in turn affects ...

Email: jonsimmons{at}doctors.org.uk AIM To determine if polymorphisms in the VDR gene are associated with susceptibility to IBD SUBJECTS European Caucasoids: 158 patients with ulcerative colitis, 245 ...

Gene expression changes were analyzed with one-way ANOVA with Tukey´s multiple comparisons ... To assess the impact of genetic risk variants on RPE cells, we used iPSC-RPE lines and used the FH Y402H ...

Figure 4. Holter tracings showing pleiomorphic and polymorphic ventricular tachycardia preceding the occurrence of ventricular fibrillation in a patient with catecholaminergic polymorphic ventricular ...

Some of the market’s biggest winners start off as the smallest players. While trillion-dollar tech giants like the ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

Solid Biosciences Inc. (Nasdaq: SLDB) (the “Company”), a life sciences company developing precision genetic medicines for ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...