These phosphorylation reactions control the activity of many enzymes involved in intracellular signaling pathways. Specifically, the addition of phosphate groups causes a conformational change in ...

Other technologies used to globally map phosphorylation in yeast by identifying ... suggesting the existence of previously unknown pathway connections. One such triple motif was found between ...

These results suggest that pp72 phosphorylation represents a novel, independent signal transduction pathway induced specifically by activation of FcєRl.

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus ... The overall goal is to understand how Syk tyrosine ...

A research group of The University of Tokyo has discovered that in mammals, a protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 (PP1) and calcineurin promote sleep. This study ...

Researchers at the University of Copenhagen have identified a signaling pathway that simultaneously increased energy expenditure and decreased food intake. In both human and primate studies, agonists ...

This valuable study investigates the signaling pathways regulating retina regeneration. Solid evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following retinal ...

Drugs that specifically inhibit BCR signaling elements are currently being ... B-cell receptor-activation pathways following antigenic stimulation. BCR: B-cell receptor; BLNK: B-cell linker ...