Pathogenesis of systolic hypertension in the elderly and clinical consequences. CKD: Chronic kidney disease; LV: Left ventricular; LVH: Left ventricular hypertrophy.

[103] ANG-II is considered to be a potential mediator of intrahepatic portal hypertension because its plasma levels are increased in cirrhosis and its administration induces a rise in portal pressure.

Hypertension, often triggered by stress, poses a serious health risk. Studies show a strong link between chronic stress and increased blood pressure, potentially leading to heart disease and stroke.

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endothelial inflammation, oxidative stress, and apoptosis by downregulating Nlrp3. This effect helps alleviate Ang II-induced hypertension in mice.

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