This technical study presents a novel sampling strategy for detecting synaptic coupling between neurons from dual pipette patch-clamp recordings in acute slices of mammalian brain tissue in vitro. The ...
In this technical paper, the authors introduce a useful variation on the fully automated multi-electrode patch-clamp recording technique for probing synaptic connections that they term "patch-walking" ...
However, the patch-clamp technique entails potential cellular trauma and relies heavily on the operator’s proficiency. Microelectrode arrays (MEAs) necessitate specialized culture dishes owing to ...