This valuable study reports on a novel role of PD-1 in early T cell differentiation, showing that PD-1 stimulation impairs Th2 differentiation more effectively than that of Th1, with implications for ...

HER2-negative gastric cancer is not favorable in patients who have PD-L1-negative tumors, as measured by a combined positive score (CPS) or tumor area positivity (TAP) score below 1. One ...

The FDA’s Oncologic Drug Advisory Committee voted against the use of checkpoint inhibitors in esophageal cancer with PD-L1 expression less than 1. In an 11 to 1 vote, the FDA’s Oncologic Drug Advisory ...

After picking apart PD-L1 subgroup data from separate phase 3 trials of BMS’ Opdivo, Merck’s Keytruda and BeiGene’s Tevimbra, the FDA found that the drugs’ benefit-risk profiles ...

The FDA’s Oncologic Drug Advisory Committee voted against the use of checkpoint inhibitors in first-line advanced gastric cancer with PD-L1 expression less than 1. In a 2 to 10 vote, the FDA’s ...

NEW YORK – The US Food and Drug Administration will ask experts in its Oncologic Drugs Advisory Committee (ODAC) on Thursday whether it should narrow two currently approved indications of checkpoint ...

Introduction: Programmed death ligand – 1 (PD-L1) expression is a well-established predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). Programmed death – 1 (PD-1) serves as ...

The following antibodies were used to stain cells: Anti-Human CD138 (MI15, 552026), Anti-Human CD47 (B6H12, #556046), Anti-Human PD-L1 (MIH1, #557924), Anti-Human CD3 (SK7, #557832), were all ...

另外，包括和铂医药、科伦博泰、百济神州等也都有退货或者被退货的经历。事实上，随着越来越多的MNC介入以及国内头部药企的加码，行业竞争也会随之加剧，这其中自然会迸发出大量机会，同时也会进行大浪淘沙的筛选。所以，越是在热闹的时候，越需要更理性的声音，越需 ...