This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...

Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903, United States ...

Radiotherapy and surgery are curative treatment options for localized prostate cancer (PCa) with a 5-year survival rate of nearly 100%. Once PCa cells spread into distant organs, such as bone, the ...

Objectives The circadian clocks are internal timing mechanisms that drive ∼24-hour rhythms in a tissue-specific manner. Many aspects of the physiology of the intervertebral disc (IVD) show clear ...

Tissue-engineered bone is mainly composed of four key components: (1) osteoblasts that can give rise to the matrix of bone tissue; (2) a biocompatible framework or scaffold from a bioactive material ...

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.

Background The pathogenesis of systemic sclerosis (SSc) involves a distinctive triad of autoimmune, vascular and inflammatory alterations resulting in fibrosis. Evidence suggests that peroxisome ...