Nucleic acid ... particular gene involved in disease is thought to be therapeutically desirable. Compared to linear mRNA, circular RNAs offer greater stability during storage and delivery, along ...

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Adeno-associated viruses (AAVs) are promising delivery tools for gene therapy and ... whereas many therapeutic nucleic acid products are smaller, leaving room for packaging additional DNA. This can be ...

The study, published online in eLife, reveals how changes in gene expression enable these small mammals ...

Nov. 22, 2024 — Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e ...

Centre for Nanostructured and Advanced Materials, DSI-CSIR Nanotechnology Innovation Centre, Council for Scientific and Industrial Research, Pretoria 0001, South Africa ...

The antibody molecules circulating in our blood and ... Analyses of alveolar macrophages’ gene-activation levels showed that the same set of genes whose activity levels differed in flu-infected mice ...

to optimize brain delivery. The PEGS summit presentation included results in preclinical models demonstrating up to 70-fold increase of amyloid-beta antibody brain exposure using the BT technology ...

zju.edu.cn Objective Accumulation of free fatty acids (FFAs) in hepatocytes induces lipotoxicity ... Partial knockdown of MPST via adenovirus delivery of MPST short hairpin RNA or heterozygous ...