Here, in bone marrow transplantation and organoid culture models, T-cell-derived Interferon-γ is shown to promote STAT1-dependent intestinal stem cell c-MYC expression and epithelial regeneration.
In this study, we demonstrate that NIC increases the abundance and proliferative activity of intestinal stem cells (ISCs) in vivo and ex vivo ... Inc., Cranbury, NJ), 100 ng/mL Noggin (PeproTech, Inc.
uea.ac.uk Background A defining characteristic of the human intestinal epithelium is that it is the most rapidly renewing tissue in the body. However, the processes underlying tissue renewal and the ...
Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.
Department of Medicine, University of Erlangen-Nuremberg, Hartmannstrasse 14, 91 054 Erlangen, Germany; christoph.becker{at}uk-erlangen.de Intestinal epithelial cells (IEC) are organised as a single ...
Whereas, all models are restricted to mice, lacking analysis of human samples or human intestinal organoids to prove the human relevance of these findings. Overall, the presented results support their ...
A: Animal; ACE: Accessory cholera enterotoxin; H: Human; ZOT: Zonula occludens toxin.
After years of controversy, stem cells are on the cusp of cures for conditions like epilepsy and type 1 diabetes. California Institute for Regenerative Medicine, Neurona Therapeutics, Vertex ...
The Oregon Stem Cell Center conducts basic and applied research in the field of Stem Cell Biology with the long term goal to harness the properties of stem cells for regenerative medicine and cell ...
Baylor College of Medicine and its clinics will be closed Tuesday, Jan. 21, due to expected hazardous weather conditions. Patients will be contacted for rescheduling.
The pelviperineal organs of the female reproductive tract form an essential cornerstone of human procreation. The system comprises the ectodermal external genitalia, the Müllerian upper-vaginal, ...