The purine/purinergic system has emerged as a fundamental regulator of cellular communication, influencing various physiological processes such as metabolism, energy balance, and signal transduction.
While most prostate cancers initially respond to androgen receptor-blocking therapies, some tumors evolve into a highly aggressive, treatment-resistant form known as neuroendocrine prostate cancer, ...
The endocrine actions of FGF23 ... In the presence of Klotho, FGF23 activates downstream signaling components that influence the homeostasis of phosphate, whereas in the absence of this membrane ...
GSVA signature scores and log2 FPKM values are colored according to scales shown on plot. AR: androgen receptor, NE neuroendocrine, EMT: epithelial-mesenchymal transition, CCP: cell cycle progression.
An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in treatment-resistant prostate cancers, according to a new study. The results could potentially lead to new therapies ...
as recent research purports that it may also be involved in broader neuroendocrine signaling and metabolic regulation. GHRP-6 Peptide: Metabolic Implications and Energy Homeostasis GHRP-6 has been ...
This cell signaling mechanism can take hours or more ... beyond the confines of sexual differentiation and reproductive neuroendocrine function. It is clear that the estrogen receptor is not ...