IL-2 and IL-15, which have a crucial role in the development and proliferation of NK cells, are also potent inducers of cytotoxicity ... dependent and cytokine mediated and are relayed through ...

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and ...

The TIMING™ platform, supported by AI, enables advanced label-free cell analysis for cancer immunotherapy. By observing ...

Following the discovery of inhibitory KIR and the understanding that they play a role in preventing NK cell killing of self MHC I-expressing tumor cells, investigators began to research the ...

Findings provide a foundation for further exploration of natural killer cells for the development of future treatments and therapies for a range of lung diseases, including chronic obstructive ...

SEM image of the membrane protrusions of normal and intratumoral NK cells. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by ...

To mediate antibody-dependent cellular cytotoxicity (ADCC), NK cells ... immunotherapy is enhancing therapeutic mAb-mediated CD16 activation of NK cells. CAR-NK cells containing multi-specific ...

A new study highlights the role of natural killer T cells in influencing the immune response to dengue virus, potentially reducing the severity of subsequent infections. As the dengue virus ...

Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

Retraction Note: Genistein inhibits stemness of SKOV3 cells induced by macrophages co-cultured with ovarian cancer stem-like cells through IL-8/STAT3 axis. Retraction Note: Hsa_circ_0001944 ...

During this process, the CD28-mediated co-stimulatory signal plays a central role ... IL-7, IL-15, IL-21, etc. 2. Enhance NK cell proliferation and cytotoxicity Studies have shown a significant ...