The F386S mutation, however, does so only in Aβ-rich regions of the cells, not in C99-rich regions, consistent with the deficiencies of this mutant enzyme only in trimming of Aβ intermediates. These ...
The diagnosis of precore mutant chronic hepatitis B (CHB) can be made with safety only by sequencing the precore region of the hepatitis B virus (HBV) genome, a method not widely available.