For both the SAD and MAD portions of the trial, pharmacodynamic markers, including pSTAT levels, were measured.

A-005 was well tolerated and demonstrated ability to cross blood-brain barrier – – Maximal TYK2 inhibition achieved with favorable pharmacokinetic profile in CNS and periphery – – Data support ...

"I thought I was dying, but little did I know it was a new beginning." Dominika shares her MS diagnosis experience and outlook on life.

Psychotic disorders are severe mental health disorders that cause abnormal thinking and perceptions. Persons with a psychotic disorder often lose touch with reality and may experience symptoms like ...

Tubeless tyres have been taken up with gusto in the pro peloton in the last few years, with a key benefit being lower rolling resistance, not to mention much easier set-up than the pros' former ...

Background Bronchiolitis caused by the respiratory syncytial virus (RSV) and its related complications are common in infants born prematurely, with severe congenital heart disease, or ...

Developing multiplex RADTs capable of diagnosing multiple respiratory viruses and bacteria is vital. Confirming in clinical trials the promising results of observational studies regarding ...