Research indicates that cannabis use causes cellular damage that increases the risk of highly cancerous tumors by disrupting ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

whereby an increase in MCU activity during odor conditioning stimulates mitochondrial calcium influx and an increase in mitochondrial reactive oxygen species (mtROS) production, triggering the release ...

To date, however, very few studies have been conducted to investigate the combined effects of anticancer drugs and radiotherapy. In this study, to evaluate the role of mitochondria-derived reactive ...

Cannabis exposure leads to genetic damage and accelerated aging, raising concerns about its transgenerational health effects ...

Conclusion: DTG-AF mice model the neurocognitive dysfunction seen in AF and display loss of myogenic tone and vascular dysfunction which may be the cause of altered cerebral autoregulation. Reducing ...

An oral presentation at the Michael J. Fox Foundation’s 16 th Annual Parkinson’s Disease Therapeutics Conference in October 2024 in New York, NY. A virtual webinar hosted by Gain Therapeutics in ...

Mitochondria play a crucial role in immune signaling pathways by releasing danger-associated molecular patterns (DAMPs), like reactive oxygen species (mtROS), ATP, and mitochondrial DNA(mtDNA), which ...