Scientists broadly agree that both apolipoprotein E and microglia are necessary ingredients for amyloidosis. In mice devoid of ApoE, or of their microglia, scant plaques form. Now, a sweeping study ...

As the global population gets older, age-related diseases are becoming more prevalent, with many linked to dysfunctional immune responses. In the central nervous system, microglia are resident immune ...

Once across, some of these travelers find themselves within the clutches of a specialized type of microglia, according to a preprint posted October 2 on bioRxiv. Through fluorescent labeling of the ...

The study is important and the data are convincing for potential microglial replacement therapy to treat retinal and CNS diseases. Microglia exhibit both maladaptive and adaptive roles in the ...

Last, Yang et al (Yang Z, et al. Echinacoside ameliorates post-stroke depression by activating BDNF signaling through modulation of Nrf2 acetylation. Phytomedicine. 2024;128:155433. doi: ...