These microglia then mount an inflammatory response ... More information: Yajuan Li et al, Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK, Cell Metabolism ...

As a result, other brain cells, called microglia ... APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size, Journal of Cell Biology (2024).

The clinical worsening after microglia envelop neurons suggests the phenomenon is harmful, the authors noted. “With disease progression, microglial behavior changes from positive to negative,” ...

Lipid deposits (green) in brain immune cells (red) from mice with Alzheimer’s-like disease all but disappear (right) after the mice are treated with an experimental drug. Researchers at ...

Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading pathogens to gobble up. But what happens when they go rogue? Historically ...

We are taught that plasma membranes are a typical lipid bilayer, but how do we know this, and who figured it out? Aa Aa Aa Most books mention that membranes have a typical "lipid bilayer," but why ...

Is the cholesterol in egg yolks the "good" or "bad" kind? Can you "burn" cholesterol by exercising? Which has more cholesterol, a tablespoon of butter or a cup of peanut butter? Most people know ...

Seipin forms a flexible cage at lipid droplet formation sites. Nat Struct Mol Biol. 2022 Feb 24. doi: 10.1038/s41594-021-00718-y. Online ahead of print. Mejhert N, Gabriel KR, Frendo-Cumbo S, Krahmer ...

There is a relationship between a person having high cholesterol levels and going on to develop dementia. People with high cholesterol levels also often have other health conditions like high blood ...

Aug. 14, 2024 — More than a quarter of Australians over the age of 50 take cholesterol-lowering drugs to prevent heart disease and strokes, but our bodies also need cholesterol to survive.

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading pathogens to gobble up. But what happens when they go rogue? Historically ...