Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the ...

In this interview, Dr. Tilman explains the functions of iPSC-derived microglia and their relevance to conditions like Alzheimer’s and other neurodegenerative diseases. Microglia are the primary ...

Our study of atherosclerotic cardiovascular diseases and hereditary lipid disorders encompasses family history, linkage studies, candidate gene-association studies, genome-wide association studies and ...

In the revised manuscript Vicario et al. provide new insights on a potential contribution of somatic mutations within the microglia population of the CNS that accelerates microglia activation and ...

However, to the best of our knowledge, there is currently a scarcity of data from investigations into the lipid metabolic profiles of microglia/macrophages in the glioma setting. Therefore, the ...

High LDL cholesterol levels (“bad cholesterol”), low HDL cholesterol levels (“good cholesterol”), and high triglyceride levels are now recognized as being major risk factors for cardiovascular disease ...

Lipids are the essential macronutrients and are a major energy source for human metabolism. Lipids (including fatty acyls, sphingolipids, glycerolipids, glycerophospholipids, prenols, sterols, ...

Quantitative profiling of reporter mouse cohorts from young to geriatric ages reveals cell- and tissue-specific alterations in mitophagy and macroautophagy between distinct subregions and cell ...