Reducing microglial activity in the presence of apolipoprotein E4 (APOE4) has uncovered a mechanism associated with the deposition of misfolded amyloid and tau in a novel mouse model of Alzheimer’s ...

Huang's group had previously found that mouse neurons producing human APOE4 release molecular signals that activate microglia. This time, they used the new mouse model to probe in more detail the ...

Huang's group previously found that mouse neurons producing human APOE4 release molecular signals that activate microglia. This time, they used the new mouse model to probe in more detail the ...

Campus Chemical Instrument Center, Mass Spectrometry & Proteomics Facility, The Ohio State University, Columbus, USA ...

In a new study from Texas A & M University College of Medicine, researchers have used a nasal spray to target microglia and ...

Huang's group had previously found that mouse neurons producing human APOE4 release molecular signals that activate microglia. This time, they used the new mouse model to probe in more detail the ...

What if fighting the onset of dementia was as simple as a few sniffs? Researchers at Texas A&M have discovered a new therapy ...

Microglia, the defence cells of the brain ... In order to understand them, they had to rely on mouse models. Although the human brain also has an SVZ, new neurons are only produced in the first ...

More information: Suvra Nath et al, Interaction between subventricular zone microglia and neural stem cells impacts the ...

Microscopic image of tissue cross-sections of a mouse brain with a glioblastoma ... in yellow and the immune cells (macrophages and microglia) adjacent to the tumor in pink.