Histone modifications play an essential role in macrophage functions. Here, we report that Cxxc finger protein 1 (CFP1), a key component of the SETD1 histone methyltransferase complex, promoted the ...

Here, we report the manufacture of new nanoformulations of nanozymes with chemically stabilized structure and improved loading capacity for the delivery of antioxidants in macrophages to disease ...

The final, formatted version of the article will be published soon. Classical swine fever (CSF) is a highly contagious disease caused by classical swine fever virus (CSFV). NS5A, a nonstructural ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

Inhibiting GLS1 reduced high blood pressure in the right side of the heart of PAH rats and improved various measures of heart ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Targeting the FGFR3/CXCR7 pathway in monocytes/macrophages could be feasible for arthritis prevention and early treatment. The protein level of FGFR3 or CXCR7 in monocytes may be a potential factor to ...

Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented.

Chair of the Department of Cell, Developmental and Cancer Biology of the Knight Cancer Institute at the Oregon Health and ...

Mitochondria, often seen as cellular powerhouses, play a surprising role in immune regulation. Researchers found that ...

Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.