Lectins are a kind of protein present in various foods such as grains, legumes, and nightshade vegetables. While they’re generally safe for consumption, some individuals may suffer from negative ...
"Most glycosylation enzymes, or glycosyltransferases, do not have an additional lectin, or sugar-recognition domain like GnT-IVa and GnT-IVb. Most glycosyltransferases only possess a catalytic ...
present a generalizable strategy utilizing CRISPR screens and lectin microarrays to identify ... Here, authors report Glycocarriers, a mammalian cell-based method for the sustainable and scalable ...
We elucidated exceptionally stable proteins, structures, and macromolecules that persist in mammalian ovaries and gametes across the reproductive lifespan. Ovaries exhibit localized structural and ...
These degrons enable degradation of both luminal and integral membrane ER proteins, expanding the types of proteins that can be targeted for degradation in budding yeast and mammalian tissue culture.
This unique find reveals a large mammal for its time, shedding light on mammalian evolution during the Late Cretaceous. The study also provides insight into the rich ecosystems of North America ...
1 Department of Medicine, Division of Gastroenterology & Hepatology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK 2 Wellcome Trust PhD Programme for Clinicians, Cambridge Institute ...
The NGL-based microarray system contains lipid-linked oligosaccharide probes, with a high content of natural oligosaccharide sequences, some of which are difficult to synthesise: the repertoire ...