The zebrafish is increasingly recognized as a model organism for translational research into human neuropathology. The zebrafish brain exhibits fundamental resemblance with human neuroanatomical and ...

Irf3 and Irf7 initiate the expression of type 1 interferons that further exacerbates the antiviral innate immune response to infection. Table 2 Table of antiviral genes studied in zebrafish models of ...

Scientists from Australia have successfully bioengineered genetically modified fruit flies and zebrafish capable of absorbing toxic mercury and releasing it back into the environment in a less ...

Danon Disease is a rare X-linked disorder caused by genetic mutations in the LAMP2 gene and the therapy works by instructing the body to express a healthy copy of the LAMP2B protein in order to ...

This important study addresses the idea that defective lysosomal clearance might be causal to renal dysfunction in cystinosis. With mostly solid data, the authors observe that restoring expression of ...