The mTOR pathway is activated in phagocytes in response to bacterial infection or following exposure to lipopolysaccharide (LPS). Unexpectedly ... of transcription 3 (STAT3), which is necessary ...
A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling.