Oncogenic KRAS activation is responsible for the most common genetic subtype of lung cancer. Although many of the major downstream signaling pathways that KRAS engages have been defined ...

Co-opted Pathways Required by Oncogenic KRAS to Sustain Lung Tumorigenesis Oncogenic KRAS relies on additional pathways that are engaged downstream of these effectors or are required indirectly as ...

Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the ...

Pancreatic ductal adenocarcinoma (PDAC) is characterized clinically by poor survival and mechanistically by KRAS- and autophagy-dependent growth. We and others previously demonstrated that inhibition ...

Discover Cardiff Oncology's promising results with Onvansertib for RAS-mutated colorectal cancer, potentially leading to ...

Erasca has streamlined its pipeline, now focusing on a phase 3 trial for Naporafenib targeting NRAS-mutant melanoma. Read ...

A mutation in the KRAS gene can lead to uncontrollable cell growth and the development of cancer. Having this mutation can significantly influence the treatment and outlook of people with colon ...

The ANCC’s global credential recognises organisations that create a supportive and empowering work environment for nurses.

ASIATODAY.ID, VIANTIANE - The ASEAN Centre for Energy (ACE) is delighted to announce the launch of the 8th edition of ...

By , SciTech Editor Exploring new research into possible anti-addiction drugs; discussing research quality and the influence ...

Martyn Irvine has said he is very much looking forward to getting stuck into his new role with Cycling Ireland following ...

Researchers hope DeepGEM can expedite targeted treatment for lung cancer patients who can't access standard genomic testing.