ORLANDO -- More than 40% of patients with longstanding prurigo nodularis (PN) had significant improvement within 3 months of ...

SASP factors secreted by senescent cells activate the JAK-STAT3 and NF-kB pathways in non-senescent tumor cells, promoting proliferation, therapy resistance and SASP spreading. Senescent tumor cells ...

Janus kinase (JAK) inhibitors look to be a good treatment option for the newly recognized, rare autoimmune disease known as ...

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway plays a key role in immune response and inflammation. More and more studies demonstrated that JAK/STAT ...

A few decades ago, hotels were supreme. They had strong relationships with their customers, who were deeply loyal to particular hotels they trusted. But that has changed with the rise of online ...

That change was linked to a rise in a modified form of cholesterol known as oxysterol. Lowering oxysterol, in both animal models and human stem cells, freed the trapped ABCA1 and restored the pathway ...

This opioid pathway in the brain was specifically activated when the mice ate additional sugar, but not when they ate normal or fatty food. When the researchers blocked this pathway, the mice ...

Pathway Sports and Entertainment, a new company “focused on monetizing athlete NIL rights,” is launching into the space by “providing players with four-figure guarantees as part of video game NIL ...

2024年9月，四川省医学科学院·四川省人民医院在Journal of Ethnopharmacology（IF4.8003/2区）上在线发表了一篇论文。在发表4个月后 ...

Convincing evidence shows that the sphingosine-1-phosphate (S1P) signaling pathway is inhibited following retinal injury ... In the current study we demonstrate that intravitreal injections of S1P ...

近日，来自复旦大学附属中山医院血液科的研究人员在《Cell Death and Disease》期刊上发表了题为 “Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway” ...