Cholangiocarcinomas are malignant tumors that derive from cholangiocytes of small intrahepatic bile ducts ... ICC), or of large hilar or extrahepatic bile ducts (extrahepatic cholangiocarcinoma ...

Multivariate analysis indicated the presence of intra- and extrahepatic recurrence as independent predictive factors for poor prognosis. Risk factors for intrahepatic recurrence were resection ...

US FDA approves Jazz Pharma’s Ziihera to treat adults with previously treated, unresectable or metastatic HER2-positive biliary tract cancer: Dublin Friday, November 22, 2024, 1 ...

Currently, chemotherapy remains a common treatment for biliary tract cancers, which have a limited survival rate.

In addition, the laboratory developed a novel method for the derivation of cholangiocytes, the specialized epithelial cells that line the intrahepatic and extrahepatic bile ducts, from induced ...

NAFLD is a multisystem disease where systemic insulin resistance and related metabolic dysfunction play a pathogenic role in the development of NAFLD and its most relevant liver-related morbidities ...

What is progressive familial intrahepatic cholestasis? Progressive familial intrahepatic cholestasis (PFIC) is a disorder that causes progressive liver disease, which typically leads to liver failure.

Although subgroup analyses should be interpreted with caution, patients with [intrahepatic cholangiocarcinoma] and [gallbladder cancer] appeared to derive greater PFS benefit from bevacizumab than ...

Combining the therapeutic approaches of GLP-1 agonists (which target extrahepatic mechanisms for metabolic disorders) with resmetirom (which target intrahepatic mechanisms for MASH and liver ...