Emerging evidence indicates a correlation between inflammation and the development and progression of cancer. Among the various inflammatory signals, interleukin-17 (IL-17 ... we introduce the ...
Interleukin-4 (IL-4) has been considered as one of the tolerogenic cytokines in many autoimmune animal models and clinical settings. Despite its role in antagonizing pathogenic Th1 responses, little ...
Scientists engineered T cells to protect instead of kill, potentially enabling targeted treatments for autoimmune disease and ...
Increland has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an interleukin-1 receptor-associated kinase 4 (IRAK-4) ...
To demonstrate the efficacy of targeting interleukin 6 receptor in patients with Sjögren’s syndrome-related systemic complications ... Results 110 patients were randomised, 55 patients to tocilizumab ...
Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan Division of Molecular Neuroimmunology, Medical Institute of Bioregulation ...
It comprehensively enhances the quality of life of patients and exhibits excellent safety. Stapokibart is a high-efficient, humanized antibody targeting the interleukin-4 receptor alpha subunit ...
28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than ... NK Cells Expressing Interleukin-21 Show Promising Antitumor Activity ...
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