Interleukin-1 receptor-associated kinase 4 is critical in the modulation of inflammatory responses through Toll-like receptor and IL-1R signaling.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. IL-2 stimulation post-transcriptionally ...

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating ...

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

At the moment, the company is developing novel therapeutic approaches for patients with underserved heart issues, such as ...

(TSX: CRDL) has seen success under a phase II trial conducted on CardiolRx, which is the company’s lead small molecule drug ...

The molecular mechanisms of HSP47 induction in intestinal fibrosis related to CD, however, remain unclear. Here we investigated the role of interleukin (IL)-17A-induced HSP47 expression in intestinal ...

Principal Financial Group Inc. reduced its position in shares of Kiniksa Pharmaceuticals, Ltd. (NASDAQ:KNSA – Free Report) by ...

Cardiol Therapeutics Inc. shares N.CRDL are trading off 7 cents at $1.76.

The US Food and Drug Administration has approved bimekizumab, a humanized interleukin (IL)-17A and IL-17F antagonist, for the ...

Data demonstrate potential superiority of a targeted protein degradation strategy compared to kinase inhibition for both BTK ...