IL-17A signals through its receptor, IL-17RA, which is expressed in many peripheral tissues; however, expression of IL-17RA in the central nervous system (CNS) and its role in CNS inflammation are ...

Interim phase 3 results showed the IL-13 monoclonal antibody improves histology and symptoms in EoE, even in participants ...

This important study provides solid in-vivo evidence that CCR4 regulates the early inflammatory response during atherosclerotic plaque formation. The authors propose that altered T-cell response plays ...

Group Inc. (OTCQX: OTCM), operator of regulated markets for trading 12,000 U.S. and international securities, today announced ...

Here, we investigated whether IVD degeneration could be induced spontaneously by the removal of the natural inhibitor of IL-1 (IL-1 receptor antagonist) in mice that lack a functional IL-1rn gene.

Surface staining was performed for 20 minutes at 4°C with fluorochrome-conjugated antibodies. Fc receptors were blocked with BD Pharmingen Purified Rat Anti ... Fluorescein isothiocyanate ...

The following is a summary of “rs6967330 minor allele in CDHR3 is a significant risk factor for severe acute exacerbations in ...

GLP-1 receptor agonists are a non-insulin type 2 diabetes medication. GLP-1 agonists help to lower blood sugar and aid in weight loss. Drugs in this class include Byetta (exenatide), Victoza ...