The hypothalamus plays a crucial role in the regulation of feeding, reward and other motivated behaviors. Elucidating neuronal circuits within the hypothalamus using animal models can expand our ...

This review highlights the key areas of research in the hypothalamic control of appetite. The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and ...

The researchers also explored how the PMd interacts with other parts of the brain, particularly the ...

At one end of the circuit are special neurons in the arcuate nucleus (Arc) region of the hypothalamus that pick up hunger signals such as the hormone leptin, which is produced by fat cells.

The findings reveal that BNC2 neurons, when activated by leptin and possibly other signals, not only suppress appetite but also alleviate the negative feelings associated with hunger. Remarkably, ...

At one end of the circuit are special neurons in the arcuate nucleus (Arc) region of the hypothalamus that pick up hunger signals such as the hormone leptin, which is produced by fat cells.