This in turn contributes to the loss of hepatocyte microvilli and sinusoidal endothelial fenestrae, which result in deterioration of hepatic function. Kupffer cell (macrophage) activation ...

You have full access to this article via your institution. Figure 2: Differential interaction of Apo2L trail versions with hepatocytes.

Hamilton and McMichael 1 and Matthews 2 have recently suggested mechanisms to explain features of intestinal disaccharide absorption which are dependent on the structure of the microvilli and ...

The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...

To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derangements associated with non-alcoholic steatohepatitis (NASH), we treated human hepatocyte cell lines ...

Total RNA was isolated using RNeasy Mini Kit (QIAGEN, Valencia, CA, United States) following the manufacturer’s guidelines. The concentration of total mRNA was assessed using a microvolume ...

The liver is a large internal organ that is under your right ribs just beneath your right lung. It has two lobes (sections). The liver is made up mainly of cells called hepatocytes. It also has other ...