A team of researchers led by Professor Ningling Kang, PhD, at The Hormel Institute, University of Minnesota, has published an ...

The paradigm of stellate cell activation provides an important ... The most effective way to eliminate hepatic fibrosis is to clear the primary cause of liver disease. The latter includes ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that drive hepatic fibrosis. These immunomodulatory, antifibrotic, and liver ...

Moreover, the cells act on hepatic stellate cells, a key driver of hepatic fibrosis. This gives such liver-derived progenitor cells anti-inflammatory and antifibrotic properties. Recognizing the ...

17 in Molecular Cell, provides new insights into a pair of proteins, called p62 and NBR1, and their opposing functions in regulating the interferon response in hepatic stellate cells, a critical ...

Learn about HMGB1's crucial role in liver diseases, its pathways and therapeutic potential that can treat liver diseases.

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be ...

Carisma Therapeutics Inc. (CARM) presented promising preclinical data on engineered macrophages for treating liver fibrosis at the ...