will be first in vivo HSC-directed therapy tested in humans Preclinical data to be presented at ASH Annual Meeting demonstrate proof-of-concept for efficient in vivo engineering of HSCs ...

These innovative programs leverage Ensoma's in vivo hematopoietic stem cell (HSC) engineering platform and aim to address critical unmet needs in chronic granulomatous disease (CGD), sickle cell ...

Lead program advancing to IND filing in H1 2025 for the treatment of X-linked chronic granulomatous disease (X-CGD) will be first in vivo HSC-directed therapy tested in humans Preclinical data to be ...

The culture system established in their study reproduces the microenvironment where HSC development occurs and ... demonstrating the method's effectiveness and potential for broader applications.

The team set out to see if they could control this by engineering plasmids with higher and higher copy numbers. To test this, the team looked at four different origins of replication used in AMTs ...

The University of Virginia has combined efforts with Johns Hopkins University and others to understand how systems affect the ...

Financial engineering is the application of engineering methods and the engineer's problem-solving skills to important problems in finance. This interdisciplinary field integrates methods and ...

The study is a collaboration with the Department of Radiation Oncology, the Radiation Treatment Program at the Sunnybrook Health Sciences Centre in Toronto, Canada, the largest cancer center in Canada ...

Impact and progress Frontiers' impact Progress Report 2022 All progress reports ...