The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate, called NMDA ...

Glycine activates receptors for the neurotransmitter glutamate, called NMDA receptors. "The genetics of schizophrenia is very complex, and it is rare that mutations found in patients can be linked ...

The mutation led to higher levels of glycine decarboxylase (GLDC), an enzyme that degrades glycine, reducing NMDA receptor activation. Mice with extra copies of the GLDC gene exhibited ...

Glycine activates receptors for the neurotransmitter glutamate, called NDMA receptors. The genetics of schizophrenia is very complex, and it is rare that mutations found in patients can be linked ...

The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate, called NDMA ...

So, that’s where Furukawa and his colleagues at CSHL will set their sights next. Discrete activation of N-methyl-D-aspartate receptor (NMDAR) subtypes by glutamate and the co-agonist glycine is ...